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Author need some maths help
vibrio
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30th Oct 05 at 20:00   View User's Profile U2U Member Reply With Quote

for my PhD I need to understand the Fourier transform in order to convert time domain data to frequency domain data.



anyone care to offere a simple explantion
MikeD
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30th Oct 05 at 20:01   View User's Profile U2U Member Reply With Quote

the answer is 3 i think
Bram
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30th Oct 05 at 20:02   View User's Profile U2U Member Reply With Quote

I'll just dig my Casio Calculator watch out..........
corsa_godfather
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30th Oct 05 at 20:04   View User's Profile U2U Member Reply With Quote

.3 x 9 6's of a decimal minus a wet sock
Graeme
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30th Oct 05 at 20:10   View Garage View User's Profile U2U Member Reply With Quote

quote:
Originally posted by MikeD
the answer is 3 i think


no its 4 mate, close but no cigar for u!!
Jake
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30th Oct 05 at 20:11   View User's Profile U2U Member Reply With Quote

care to ellaborate the equation?
Ian
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30th Oct 05 at 20:11   View Garage View User's Profile U2U Member Reply With Quote

quote:
Originally posted by vibrio
anyone care to offere a simple explantion
Yes, the peaks on your time graph are what will feature in your distribution.
vibrio
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30th Oct 05 at 20:17   View User's Profile U2U Member Reply With Quote

quote:
Originally posted by jake
care to ellaborate the equation?


not got a scooby the computer does it all for you when you get the readings from the NMR machine but felt I should at least try to understand it. you get the info from the NMR as a sin wave and the FT changes that into a graph with peaks to give you your spectra




Modern pulse NMR is performed exclusively in the Fourier transform mode. Of course it is useful to appreciate the advantages of the transform, and particularly the spectacular results which can be achieved by applying it in more than one dimension, but it is also essential to understand the limitations imposed by digital signal analysis. The sampling of signals, and their manipulation by computer, often limit the accuracy of various measurements of frequency and amplitude, and may even prevent the detection of signals altogether in certain cases. These are not difficult matters to understand, but they often seem rather abstract to newcomers to FT NMR. Even if you do not intend to operate a spectrometer, it is irresponsible not to acquire some familiarity with the interaction between parameters such as acquisition time and resolution, or repetition rate, relaxation times and signal intensity. Many errors in the use of modern NMR arise because of a lack of understanding of its limitations

[Edited on 30-10-2005 by vibrio]
Ian
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30th Oct 05 at 20:23   View Garage View User's Profile U2U Member Reply With Quote

quote:
Originally posted by vibrio
it is irresponsible to try and acquire some familiarity with the interaction between parameters such as acquisition time and resolution, or repetition rate, relaxation times and signal intensity on a car web site.
Yeah, big problem.
vibrio
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30th Oct 05 at 20:26   View User's Profile U2U Member Reply With Quote

quote:
Originally posted by Ian
quote:
Originally posted by vibrio
it is irresponsible to try and acquire some familiarity with the interaction between parameters such as acquisition time and resolution, or repetition rate, relaxation times and signal intensity on a car web site.
Yeah, big problem.



LMFAO - to be fair I only posted it because of

quote:
Originally posted by Ian
I was just getting in to that



next time I'll not bother trying
Jake
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30th Oct 05 at 20:26   View User's Profile U2U Member Reply With Quote

what's the verdict, Ian?
Ian
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30th Oct 05 at 20:27   View Garage View User's Profile U2U Member Reply With Quote

What the hell are you sampling anyway?
vibrio
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30th Oct 05 at 20:32   View User's Profile U2U Member Reply With Quote

quote:
Originally posted by Ian
What the hell are you sampling anyway?



protein called MBD2 whic forms part of the MeCP1 protein complex which specifically binds methylated CpG DNA sequence- which has implication in cancer as when you knock it out rates are resistant to developing cancer downside is they become bad mothers lol. if you can show how it binds to the DNA you can design a drug to block it.

[Edited on 30-10-2005 by vibrio]
Dan B
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31st Oct 05 at 00:19   View User's Profile U2U Member Reply With Quote

http://mathworld.wolfram.com/FourierTransform.html
Edd
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1st Nov 05 at 12:46   View User's Profile U2U Member Reply With Quote

maths my only weakness

 
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